1. The capital of St. Helena in the southern Atlantic Ocean.
2. A former village of southeast Virginia, the first permanent English settlement in America. It was founded in May 1607 and named for the reigning monarch, James I. Jamestown became the capital of Virginia after 1619 but was almost entirely destroyed during Bacon's Rebellion (1676) and further declined after the removal of the capital to Williamsburg (1698-1700).
3. A city of western New York on Chautauqua Lake near the Pennsylvania border. It is the trade center of a farming and grape-producing region.