systemic lupus er·y·the·ma·to·sus (ĕr′ə-thē′mə-tōsĭs)
n. Abbr. SLE
An inflammatory autoimmune disease that affects multiple organ systems, usually characterized by fatigue, fever, skin lesions, joint pain and swelling, and anemia, and often affecting the kidneys and various other organs. It is much more common in women than in men.
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