1. A letter, especially a formal one. See Synonyms at letter.
2. A literary composition in the form of a letter.
3. Epistle Bible
a. One of the letters included as a book in the New Testament.
b. An excerpt from one of these letters, read as part of a religious service.
[Middle English epistel, from Old French epistle, from Latin epistola, from Greek epistolē, from epistellein, to send a message to : epi-, epi- + stellein, to send; see stel- in the Appendix of Indo-European roots.]
The American Heritage® Dictionary of the English Language, Fifth Edition copyright ©2018 by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
The American Heritage Dictionary Blog
Check out our blog, updated regularly, for new words and revised definitions, interesting images from the 5th edition, discussions of usage, and more.
American Heritage Dictionary Products
The American Heritage Dictionary, 5th Edition
The American Heritage Dictionary of Idioms
The American Heritage Roget's Thesaurus
Curious George's Dictionary
The American Heritage Children's Dictionary
The American Heritage Dictionary of Indo-European Roots
The American Heritage Student Grammar Dictionary
The American Heritage Desk Dictionary + Thesaurus
The American Heritage Science Dictionary
The American Heritage Dictionary of Business Terms
The American Heritage Student Dictionary
The American Heritage Essential Student Thesaurus